Abstract Background Non-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk.For many loci, however, the mechanisms through which non-coding variants influence diabetes susceptibility are Kratom unknow
Background: There is a need for tools in primary care to support clinicians to identify patients with unmet palliative care needs.The Boxers Supportive and Palliative Care Indicators Tool (SPICT) is concise and covers most conditions in primary care settings.However, the SPICT was not available in Japanese.Methods: The translation and cultural adap
Air temperatures in the tropical Andes have risen at an accelerated rate relative to the global average over recent decades.However, the effects of climate change on Andean lakes, which are vital to sustaining regional biodiversity and serve as an important water resource to local populations, remain largely unknown.Here, we show that recent climat
Abstract Increasing numbers of individuals have access to cannabinoid-based products containing various amounts of delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids.Exposure to specific cannabinoids likely influences outcomes; however, current methods for quantifying cannabis exposure do not account for the cannabinoid c
Social interactions in insects are driven by conspecific chemical signals that are detected via olfactory and gustatory neurons.Odorant binding proteins (Obps) transport volatile odorants to chemosensory receptors, but their effects on behaviors remain poorly characterized.Here, we report that RNAi knockdown of Obp56h gene expression in Drosophila